Severity of post-cardiac surgery acute kidney injury and long-term mortality: is chronic kidney disease the missing link?
نویسنده
چکیده
While the retrospective cohort study by Lopez-Delgado and colleagues [1] suggests a strong association of the RIFLE classification and long-term mortality of acute kidney injury (AKI) after post-cardiac surgery, it has a number of limitations. The numbers of patients with pre-existing chronic kidney disease (CKD) or with nonrecovery of renal function, de novo CKD or progression of CKD to stage V are not given. The authors used an obsolete definition of CKD and a modified RIFLE classification system for definition and grading of AKI. Taken together, numerous studies underscore the strong association between AKI and de novo CKD. Severity, duration and frequency of AKI as well as age, comorbidities and pre-existing CKD are known risk fac-
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